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New Amsterdam Genomics
New Amsterdam Genomics Whole Exome Sequencing
$349
8.5/10
8.5/10
Spanwise Verdict
New Amsterdam Genomics offers one of the most accessible whole exome sequencing tests on the market. Unlike consumer SNP-based tests (23andMe, Ancestry), whole exome sequencing reads the actual DNA code of all protein-coding genes, detecting rare variants that chip-based tests miss. This is the same technology used in clinical genetics labs, now available direct-to-consumer at a fraction of traditional costs.
Best for:Comprehensive genetic screeningDisease risk assessmentPharmacogenomics
Overview
Clinical-grade whole exome sequencing that analyzes all 20,000+ protein-coding genes — providing comprehensive genetic insights for disease risk, carrier status, and pharmacogenomics.
Pros
- True whole exome sequencing — not SNP genotyping
- Analyzes all 20,000+ protein-coding genes for comprehensive coverage
- Identifies rare pathogenic variants missed by consumer SNP tests
- Includes pharmacogenomics for medication response insights
- One-time test with lifetime relevance — your DNA doesn't change
Cons
- Results require genetic counseling to interpret properly
- May uncover variants of uncertain significance (VUS) that create ambiguity
- Does not include non-coding regions (introns) — whole genome sequencing covers more
- Can reveal unexpected findings (incidental findings) that may cause anxiety