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GRAIL

GRAIL Galleri Test

$949
8.2/10
8.2/10

Spanwise Verdict

The Galleri test represents a paradigm shift in cancer screening. Standard screening only covers 5 cancer types (breast, cervical, colon, lung, prostate). Galleri screens for 50+ types through a single blood draw, including deadly cancers like pancreatic, ovarian, and liver that are typically caught too late. Sensitivity is highest for advanced cancers and lower for early-stage disease — it complements, rather than replaces, standard screening.

Best for:Cancer screeningAdults 50+Family history of cancer

Overview

Multi-cancer early detection blood test that screens for over 50 cancer types by analyzing cell-free DNA fragments shed by tumors — including cancers with no standard screening test.

Biomarkers Included

Hover over any biomarker to learn more about what it measures and why it matters.

Pros

  • Screens for 50+ cancer types — most have no other screening test
  • Simple blood draw — no imaging or procedures required
  • High specificity (99.5%) means very low false positive rate
  • Can identify cancer signal origin to guide follow-up

Cons

  • Sensitivity for early-stage (Stage I) cancers is relatively low (~17%)
  • High cost at $949 — not covered by most insurance
  • Does not replace standard screening for breast, colon, cervical, lung, or prostate cancer
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