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Genetic
APOE Genotype
Apolipoprotein E gene variants (ε2, ε3, ε4) — the strongest common genetic risk factor for Alzheimer's disease.
Optimal Range
ε3/ε3 (neutral risk) · ε4 carriers at elevated risk
Why It Matters
Carrying one APOE4 allele increases Alzheimer's risk ~3x; two copies increase it ~12x. Knowing your APOE status enables aggressive preventive strategies including metabolic optimization, exercise, sleep, and early monitoring.